Shrimp Casserole

| Posted on:

January 9, 2026

Delicious shrimp casserole baked with creamy sauce and topped with breadcrumbs

Every now and then, a recipe comes along that truly impresses friends and family but is surprisingly simple to prepare. Shrimp Casserole is one of those gems. This dish showcases the sweet, succulent flavors of large shrimp combined with creamy cheeses, all baked to perfection. Whether it’s for a special gathering or a cozy weeknight dinner, this recipe offers a delightful blend of convenience and taste, effortlessly bringing people together around the dinner table.

Why you’ll love this dish

Shrimp Casserole is not only delicious but also incredibly versatile and quick to make. With just a handful of ingredients and straightforward steps, this recipe is perfect for all occasions. It’s an ideal dish for busy weeknights or casual get-togethers, making it a go-to favorite for many home cooks. The creamy texture melded with the light crunch of panko breadcrumbs creates a satisfying meal that both kids and adults will enjoy.

"I made this for a family gathering, and everyone raved about it! It’s so rich and comforting yet super easy to throw together."

Step-by-step overview

Making Shrimp Casserole is a breeze when you break it down. Start by boiling your shrimp until they’re perfectly cooked, then mix them with creamy ingredients and cheese. Once combined, transfer the mixture to a buttered dish, top it with crispy panko, and bake until bubbly. Before you know it, you’ll have a decadent casserole that feels gourmet but takes minimal effort.

What you’ll need

Gather these items to create your Shrimp Casserole masterpiece:

  • 2 pounds large shrimp (21–24 count), peeled and deveined
  • 1 tablespoon Old Bay seasoning
  • 1 tablespoon salt (for the cooking water)
  • 2/3 cup mayonnaise (or plain Greek yogurt)
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon ground black pepper
  • 1 tablespoon butter (plus more to grease the pan)
  • 1/2 cup panko bread crumbs
  • 4 ounces shredded mozzarella cheese
  • 4 ounces shredded medium cheddar cheese

Feel free to swap mayonnaise for Greek yogurt for a lighter touch, or adjust the cheese amounts according to your preferences.

Directions to follow

  1. Preheat your oven to 375°F (190°C) and butter a 2 1/2-quart casserole dish.
  2. In a large pot, bring water to a rolling boil. Add salt and Old Bay seasoning.
  3. Cook the shrimp in the boiling water until they turn opaque, about 30 seconds. Drain and transfer them into a mixing bowl.
  4. Into the bowl, add mayonnaise, garlic powder, and black pepper. Mix until the shrimp are lightly coated.
  5. Gently fold in the mozzarella and cheddar cheese until they’re evenly distributed.
  6. Spread the shrimp and cheese mixture into the prepared casserole dish.
  7. Melt the remaining butter and stir it with the panko bread crumbs. Sprinkle the mixture over the top of the casserole.
  8. Bake uncovered for 13 to 15 minutes until bubbly and the shrimp reaches an internal temperature of 145°F.
  9. For a golden touch, broil for 1 to 2 minutes, but keep an eye on it to prevent burning.
  10. Allow to rest for 15 minutes before serving.

Shrimp Casserole

Best ways to enjoy it

Your Shrimp Casserole is ready to impress! Serve it straight from the oven, garnished with a sprinkle of fresh parsley for color. Complement this dish with a crisp side salad, roasted vegetables, or fluffy rice to soak up the cheesy goodness. For a complete meal, pair it with crusty bread or a light, zesty coleslaw.

Storage and reheating tips

To keep your leftovers fresh, store any uneaten casserole in an airtight container in the refrigerator for up to three days. Reheat individual servings in the microwave or warm the entire dish in the oven at 350°F until heated through. If you plan to store it long-term, you can freeze the unbaked casserole for up to two months. Just cover it tightly with plastic wrap and aluminum foil. When you’re ready to enjoy, bake from frozen, adding a few extra minutes to the cooking time.

Helpful cooking tips

To elevate your Shrimp Casserole even further, consider adding a dash of your favorite hot sauce for a spicy kick, or mix in some fresh herbs like dill or cilantro for added flavor. When boiling the shrimp, be careful not to overcook them; they should be bright pink and firm. If you prefer a bit more texture, you can also add in vegetables like spinach or bell peppers.

Creative twists

There are many ways to customize this Shrimp Casserole. If you’re looking for a different flavor profile, swap the Old Bay seasoning for Cajun or Creole spices for a southern twist. You can also experiment with different types of cheese or add a layer of sautéed mushrooms for an earthy note. For a lighter version, consider using cauliflower rice instead of the cheese base for a low-carb option.

Common questions

What is the prep time for this recipe?

The prep time for Shrimp Casserole is approximately 30 minutes, with a cooking time of around 15 minutes.

Can I make this dish in advance?

Yes, you can prepare the casserole ahead of time and store it in the refrigerator before baking. Just cover it tightly with foil until you’re ready to bake.

How do I store leftovers?

Refrigerate any leftovers in an airtight container for up to three days. You can also freeze the unbaked casserole for longer storage.

This Shrimp Casserole recipe combines ease and elegance, making it a standout choice for any occasion! Enjoy the delightful flavors and the warmth of home-cooked comfort.

Delicious shrimp casserole baked with creamy sauce and topped with breadcrumbs

Shrimp Casserole

A delightful Shrimp Casserole featuring succulent large shrimp and creamy cheeses, perfectly baked for a comforting meal that impresses any gathering.
Prep Time 30 minutes
Cook Time 15 minutes
Total Time 45 minutes
Servings: 6 servings
Course: Dinner, Main Course
Cuisine: American, Seafood
Calories: 400

Ingredients
  

Main Ingredients
  • 2 pounds large shrimp (21–24 count), peeled and deveined
  • 1 tablespoon Old Bay seasoning
  • 1 tablespoon salt (for the cooking water)
  • 2/3 cup mayonnaise (or plain Greek yogurt) Greek yogurt can be used for a lighter version.
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon ground black pepper
  • 1 tablespoon butter (plus more to grease the pan)
  • 1/2 cup panko bread crumbs
  • 4 ounces shredded mozzarella cheese
  • 4 ounces shredded medium cheddar cheese

Method
 

Preparation
  1. Preheat your oven to 375°F (190°C) and butter a 2 1/2-quart casserole dish.
  2. In a large pot, bring water to a rolling boil. Add salt and Old Bay seasoning.
  3. Cook the shrimp in the boiling water until they turn opaque, about 30 seconds. Drain and transfer them into a mixing bowl.
  4. Into the bowl, add mayonnaise, garlic powder, and black pepper. Mix until the shrimp are lightly coated.
  5. Gently fold in the mozzarella and cheddar cheese until they’re evenly distributed.
  6. Spread the shrimp and cheese mixture into the prepared casserole dish.
  7. Melt the remaining butter and stir it with the panko bread crumbs. Sprinkle the mixture over the top of the casserole.
Baking
  1. Bake uncovered for 13 to 15 minutes until bubbly and the shrimp reaches an internal temperature of 145°F.
  2. For a golden touch, broil for 1 to 2 minutes, but keep an eye on it to prevent burning.
  3. Allow to rest for 15 minutes before serving.

Nutrition

Serving: 1Calories: 400kcalCarbohydrates: 15gProtein: 30gFat: 25gSaturated Fat: 10gSodium: 900mgSugar: 2g

Notes

Serve garnished with fresh parsley. Pairs well with a crisp side salad or roasted vegetables.

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